Genetic screening

The process of investigating an individual or group of persons to detect the presence of disease or defective genes that can be transmitted to offsprings. Women are routinely offered a variety of genetic screening tests during their first three months of pregnancy to evaluate the risk for genetic disorders in their unborn baby. The first trimester screening tests are usually done between the 10th and 13th week of pregnancy. We take every care to ensure that the baby born to you is healthy and happy. The role of genetics in assisted reproductive technology (ART) is to optimize a couple’s chance of having a healthy baby. Some forms of infertility, particularly male infertility, have a genetic basis. Couples with these forms of infertility may be at increased risk for transferring infertility to their offspring, for having a miscarriage or for having a child with a serious genetic condition. Other patients may be at increased risk for having a baby with a genetic condition based on their family history, ethnic background or age.

PGD (Pre implantation Genetic Diagnosis)
Preimplantation genetic diagnosis (PGD) involves testing for specific genetic conditions prior to the implantation of an embryo in the uterine wall. The purpose of PGD is to identify what are considered to be abnormal embryos in order to select the most desirable embryos for implantation. PGD may also be used as a form of gender selection to avoid having a child with a sex-linked disease. PGD quickly came to be used for three main groups of inherited disease:

Single-gene mutations such as cystic fibrosis and sickle cell anemia.
Sex-linked disorders such as hemophilia.
Chromosomal abnormalities such as Down syndrome.

PGS (Pre Implantation Genetic Screening)
Preimplantation Genetic Screening (PGS) is a screening test used to determine if genetic or chromosomal disorders are present in embryos produced through In-vitro Fertilization (IVF). All 23 chromosome pairs are screened during preimplantation genetic screening (PGS), also known as preimplantation genetic testing for aneuploidy (PGT-A), which enables researchers investigating in vitro fertilization to gain important knowledge about the chromosomal condition of an embryo. Embryo aneuploidy, or embryos having an aberrant number of chromosomes, can occasionally be the cause of IVF failure. Any embryo can become aneuploid, although the likelihood rises with maternal age.